Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study : implications for large-scale biomonitoring studies

Stéphanie Vandentorren 1 Florence Anna Zeman 2 Lise Morin 1 Hélène Sarter 1 Marie-Laure Bidondo 1 Amivi Oleko 1 Henri Leridon 3
1 Institut National de Veille Sanitaire
2 INERIS - Institut National de l'Environnement Industriel et des Risques
3 INED - Institut national d'études démographiques
Abstract : Exposure to phthalates and Bisphenol A could cause developmental and reproductive toxicity. This study provides a first assessment of these exposures for more than 250 French pregnant women. The median concentrations of total and free Bisphenol A in urine were similar to those in other studies except the highest concentrations (5% of women had total and free Bisphenol A >50 micro g/L). Our study highlights high levels of Di-(2-ethylhexyl)-phthalate metabolites in pregnant women, suggesting recent exposure, probably in hospital. Differences between types of delivery (caesarean vs. natural) support this hypothesis. This is a significant implication for large-scale biomonitoring studies among this population.
Keywords : BISPHENOL A PHTALATES BIOMONITORING PREGNANCY MATERNAL EXPOSURE EPIDEMIOLOGY
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Journal articles
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Submitted on : Friday, March 21, 2014 - 2:22:53 PM
Last modification on : Thursday, July 18, 2019 - 1:47:54 AM

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INERIS | INED | UNIV-HESAM | CAMPUS-CONDORCET

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Stéphanie Vandentorren, Florence Anna Zeman, Lise Morin, Hélène Sarter, Marie-Laure Bidondo, et al.. Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study : implications for large-scale biomonitoring studies. Environmental Research, Elsevier, 2011, 111 (6), pp.761-764. ⟨10.1016/j.envres.2011.05.018⟩. ⟨ineris-00963307⟩

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