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Journal articles
Applications in environmental risk assessment of leucocyte apoptosis, necrosis and respiratory burst analysis on the European bullhead, Cottus sp
Abstract : The use of a biochemical multi-biomarker approach proved insufficient to obtain clear information about ecosystem health. The fish immune system is considered as an attractive non-specific marker for environmental biomonitoring which has direct implications in individual fitness and population growth. Thus, the present work proposes the use of fish immunomarkers together with more common biochemical biomarkers in sampling conditions optimized to reduce biomarker variability and increase parameter robustness. European bullheads (Cottus sp.) from 11 stations in the Artois-Picardie watershed (France) were sampled. In the multiple discriminant analysis, the sites were highly correlated with apoptosis, respiratory burst, GST and EROD activities. Moreover, the use together of biochemical and immune markers increased the percentage of fish correctly classed at each site and enhanced site separation. This study argues in favor of the utilization of apoptosis, necrosis and respiratory burst for the determination of environmental risk assessment in addition to the set of biochemical biomarkers commonly used in fish.
https://hal-ineris.archives-ouvertes.fr/ineris-00963517
Contributor : Gestionnaire Civs <>
Submitted on : Friday, March 21, 2014 - 2:32:59 PM
Last modification on : Thursday, June 4, 2020 - 10:36:02 PM
Contributor : Gestionnaire Civs <>
Submitted on : Friday, March 21, 2014 - 2:32:59 PM
Last modification on : Thursday, June 4, 2020 - 10:36:02 PM