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Silica and silicosis mechanism. The role of surface properties of particles and of the silica-supported iron

S. Dzwigaj H. Pezerat Agnès Wastiaux 1 Patrick Sebastien 1
1 INERIS - Institut National de l'Environnement Industriel et des Risques
Abstract : In silicosis, like in coal-worker pneumoconiosis, it appears that inhalation of dusts induces a recruitment of phagocytic cells, particulariy of macrophages and an activation of these cells with correlatively oxidative burst and release of a battery of immune, proinflammatory and profibrotic mediatons in alveolar structure.
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Contributor : Gestionnaire Civs <>
Submitted on : Wednesday, April 2, 2014 - 3:31:36 PM
Last modification on : Wednesday, April 2, 2014 - 3:31:36 PM

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  • HAL Id : ineris-00969611, version 1
  • INERIS : PU-1992-075

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S. Dzwigaj, H. Pezerat, Agnès Wastiaux, Patrick Sebastien. Silica and silicosis mechanism. The role of surface properties of particles and of the silica-supported iron. 8. International Conference on Occupational Lung Diseases, Sep 1992, Prague, Czech Republic. pp.1186-1191. ⟨ineris-00969611⟩

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