State of the art in issues of uncertainty and variability for PBPK model applications - Archive ouverte HAL Access content directly
Conference Papers Year :

State of the art in issues of uncertainty and variability for PBPK model applications

(1)
1

Abstract

Issues of uncertainty and variability are of significant importance to risk assessment. This paper describes briefly the past and current practices devised to deal with those issues when making predictions with PBPK models, the strengths and limitations of those practices; the currently considered best pratices - and under what conditions they should be used - and finally what is needed (e.g., research, data, software, reporting/documentation standards, etc.) to further improve and expand the use of such models in the future.
Not file

Dates and versions

ineris-00970144 , version 1 (02-04-2014)

Identifiers

Cite

Frédéric Y. Bois. State of the art in issues of uncertainty and variability for PBPK model applications. International workshop on uncertainty and variability in physiologically based pharmacokinetic models, Oct 2006, United States. ⟨ineris-00970144⟩

Collections

INERIS
27 View
0 Download

Share

Gmail Facebook Twitter LinkedIn More