Involvement of an oxidative action in HSP70 promoter induction by three selected environmental pollutants : protective effect of n-acetylcysteine

Abstract : A number of environmentally relevant physical and chemical agents are known to induce a set of cellular stress proteins, the heat-shock proteins (HSP). This induction is mediated by a mechanism of toxicity which involves the generation ofdenatured proteins by Stressor agents. however little is known about how this denaturation occurs.