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Involvement of an oxidative action in HSP70 promoter induction by three selected environmental pollutants : protective effect of n-acetylcysteine

Selim Ait-Aissa 1 Jean-Marc Porcher 1 André-Patrick Arrigo 2 Claude Lambre 1
1 INERIS - Institut National de l'Environnement Industriel et des Risques
2 CGPhiMC - Centre de génétique et de physiologie moléculaire et cellulaire
Abstract : A number of environmentally relevant physical and chemical agents are known to induce a set of cellular stress proteins, the heat-shock proteins (HSP). This induction is mediated by a mechanism of toxicity which involves the generation ofdenatured proteins by Stressor agents. however little is known about how this denaturation occurs.
Keywords : IN VITRO OXIDATIVE STRESS HSP GENE EXPRESSION
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Conference papers
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https://hal-ineris.archives-ouvertes.fr/ineris-00976283
Contributor : Gestionnaire Civs <>
Submitted on : Wednesday, April 9, 2014 - 4:53:00 PM
Last modification on : Wednesday, November 20, 2019 - 2:40:54 AM

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  • HAL Id : ineris-00976283, version 1

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INERIS | CNRS | CGPHIMC | UNIV-LYON1 | UDL

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Selim Ait-Aissa, Jean-Marc Porcher, André-Patrick Arrigo, Claude Lambre. Involvement of an oxidative action in HSP70 promoter induction by three selected environmental pollutants : protective effect of n-acetylcysteine. 37. European Congress of Toxicology (EUROTOX 1999), Jun 1999, Oslo, Norway. ⟨ineris-00976283⟩

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