R. S. Anderson and L. L. Brubacher, Inhibition by pentachlorophenol of production of reactive-oxygen intermediates by medaka phagocytic blood cells, Marine Environmental Research, vol.35, issue.1-2, pp.125-129, 1993.
DOI : 10.1016/0141-1136(93)90025-U

A. Bado-nilles, C. Quentel, M. L. Auffret, S. Floch, T. Renault et al., Immune effects of HFO on European sea bass, Dicentrarchus labrax, and Pacific oyster, Crassostrea gigas, Ecotoxicology and Environmental Safety, vol.72, issue.5, pp.1446-1454, 2009.
DOI : 10.1016/j.ecoenv.2009.04.001
URL : https://hal.archives-ouvertes.fr/hal-00638198

A. Bado-nilles, C. Quentel, H. Thomas-guyon, and S. Le-floch, Effects of two oils and 16 pure polycyclic aromatic hydrocarbons on plasmatic immune parameters in the European sea bass, Dicentrarchus labrax (Linn??), Toxicology in Vitro, vol.23, issue.2, pp.235-241, 2009.
DOI : 10.1016/j.tiv.2008.12.001

A. Bado-nilles, S. Jolly, J. Porcher, O. Palluel, A. Geffard et al., Applications in environmental risk assessment of leucocyte apoptosis, necrosis and respiratory burst analysis on the European bullhead, Cottus sp., Environmental Pollution, vol.184, pp.9-17, 2014.
DOI : 10.1016/j.envpol.2013.07.049
URL : https://hal.archives-ouvertes.fr/ineris-00963517

J. Blasiak, Changes in membrane fluidity evoked by organophosphorus insecticide bromfenvinfos and its methylated analogue, Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, vol.110, issue.1, pp.15-21, 1995.
DOI : 10.1016/0742-8413(94)00082-L

N. C. Bols, J. L. Brubacher, R. C. Ganassin, and L. E. Lee, Ecotoxicology and innate immunity in fish, Developmental & Comparative Immunology, vol.25, issue.8-9, pp.853-873, 2001.
DOI : 10.1016/S0145-305X(01)00040-4

S. K. Bopp, H. K. Abicht, and K. Knauer, Copper-induced oxidative stress in rainbow trout gill cells, Aquatic Toxicology, vol.86, issue.2, pp.197-204, 2008.
DOI : 10.1016/j.aquatox.2007.10.014

T. J. Bowden, K. D. Thompson, A. L. Morgan, R. M. Gratacap, and S. Nikoskelainen, Seasonal variation and the immune response: A fish perspective, Fish & Shellfish Immunology, vol.22, issue.6, pp.695-706, 2007.
DOI : 10.1016/j.fsi.2006.08.016

F. Bucher and R. Hofer, Histological and enzyme histochemical changes in the kidney of male bullhead (Cottus gobio) during the spawning period, Journal of Fish Biology, vol.32, issue.3, pp.403-409, 1993.
DOI : 10.1146/annurev.bi.40.070171.002111

E. A. Carlson, Y. Li, and J. T. Zelikoff, Suppressive effects of benzo[a]pyrene upon fish immune function: Evolutionarily conserved cellular mechanisms of immunotoxicity, Marine Environmental Research, vol.58, issue.2-5, pp.2-5, 2004.
DOI : 10.1016/j.marenvres.2004.03.023

M. L. Danion, S. Floch, R. Kanan, F. Lamour, and C. Quentel, Effects of in vivo chronic hydrocarbons pollution on sanitary status and immune system in sea bass, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00905572

, Aquatic Toxicology, vol.10534, pp.300-311

M. L. Danion, S. Floch, J. Castric, F. Lamour, J. Cabon et al., Effect of chronic exposure to pendimethalin on the susceptibility of rainbow trout, Oncorhynchus mykiss L., to viral hemorrhagic septicemia virus (VHSV), Ecotoxicology and Environmental Safety, vol.79, pp.28-34, 2012.
DOI : 10.1016/j.ecoenv.2012.01.018

C. Dautremepuits, S. Betoulle, S. Paris-palacios, and G. Vernet, Immunology-Related Perturbations Induced by Copper and Chitosan in Carp (Cyprinus carpio L.), Archives of Environmental Contamination and Toxicology, vol.47, issue.3, pp.370-378, 2004.
DOI : 10.1007/s00244-004-3115-0

J. Dorts, P. Kestemont, P. A. Marchand, W. Hollander, M. L. Thezenas et al., Ecotoxicoproteomics in gills of the sentinel fish species, Cottus gobio, exposed to perfluorooctane sulfonate (PFOS), Aquatic Toxicology, vol.103, issue.1-2, pp.1-8, 2011.
DOI : 10.1016/j.aquatox.2011.01.015

M. Dunier and A. K. Siwicki, Effects of pesticides and other organic pollutants in the aquatic environment on immunity of fish: a review, Fish & Shellfish Immunology, vol.3, issue.6, pp.423-438, 1993.
DOI : 10.1006/fsim.1993.1042

A. E. Ellis, Immunity to bacteria in fish, Fish & Shellfish Immunology, vol.9, issue.4, pp.291-308, 1999.
DOI : 10.1006/fsim.1998.0192

R. Gabbianelli, G. Falcioni, C. Nasuti, and F. Cantalamessa, Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: reduction of fluidity in the hydrophobic core and in glutathione peroxidase activity, Toxicology, vol.175, issue.1-3, pp.1-3, 2002.
DOI : 10.1016/S0300-483X(02)00058-6

C. Gauvrit, Effects of the herbicides benzoylpropethyl and flampropisopropyl on rat liver mitochondria: An alteration in membrane fluidity?, Pesticide Biochemistry and Physiology, vol.21, issue.3, pp.377-384, 1984.
DOI : 10.1016/0048-3575(84)90106-8

G. C. Grinwis, A. D. Vethaak, P. W. Wester, and J. G. Vos, Toxicology of environmental chemicals in the flounder (Platichthys flesus) with emphasis on the immune system: field, semi-field (mesocosm) and laboratory studies, Toxicology Letters, vol.112, issue.113, pp.112-113, 2000.
DOI : 10.1016/S0378-4274(99)00239-8

E. Holtzman, , p.445, 1989.

P. A. Janssen, J. G. Lambert, and H. J. Goos, The annual ovarian cycle and the influence of pollution on vitellogenesis in the flounder, Pleuronectes flesus, Journal of Fish Biology, vol.52, issue.3, pp.509-523, 1995.
DOI : 10.2331/suisan.52.1847

S. Jolly, A. Bado-nilles, F. Lamand, C. Turies, E. Chadili et al., Multi-biomarker approach in wild European bullhead, Cottus sp., exposed to agricultural and urban environmental pressures: Practical recommendations for experimental design, Chemosphere, vol.87, issue.7, pp.675-683, 2012.
DOI : 10.1016/j.chemosphere.2011.12.055
URL : https://hal.archives-ouvertes.fr/ineris-00961775

L. C. Kreutz, L. J. Gil-barcellos, A. Marteninghe, E. Davi-dos-santos, and R. Zanatta, Exposure to sublethal concentration of glyphosate or atrazine-based herbicides alters the phagocytic function and increases the susceptibility of silver catfish fingerlings (Rhamdia quelen) to Aeromonas hydrophila challenge, Fish & Shellfish Immunology, vol.29, issue.4, pp.694-697, 2010.
DOI : 10.1016/j.fsi.2010.06.003

L. C. Kreutz, L. J. Gil-barcellos, S. De-faria-valle, and . De,

M. Pivato and R. Zanatta, Altered hematological and immunological parameters in silver catfish (Rhamdia quelen) following short term exposure to sublethal concentration of glyphosate, Fish & Shellfish Immunology, vol.30, issue.1, pp.51-57, 2011.

G. Krumschnabel, C. Manzl, C. Berger, and B. Hofer, Oxidative stress, mitochondrial permeability transition, and cell death in Cu-exposed trout hepatocytes, Toxicology and Applied Pharmacology, vol.209, issue.1, pp.62-73, 2005.
DOI : 10.1016/j.taap.2005.03.016

B. Lofts, G. E. Pickford, and J. W. Atz, Effects of methyl testosterone on the testes of a hypophysectomized cyprinodont fish, Fundulus heteroclitus, General and Comparative Endocrinology, vol.6, issue.1, pp.74-88, 1966.
DOI : 10.1016/0016-6480(66)90109-2

A. Luna-acosta, T. Renault, H. Thomas-guyon, N. Faury, D. Saulnier et al.,

P. Pardon, I. Fruitier-arnaudin, and P. Bustamante, Detection of early effects of a single herbicide (diuron) and a mix of herbicides and pharmaceuticals (diuron, isoproturon, ibuprofen) on immunological parameters of Pacific oyster (Crassostrea gigas) spat, Chemosphere, vol.87, issue.11, pp.1335-1340, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00686855

I. D. Mccarthy and L. A. Fuiman, Growth and protein metabolism in red drum (Sciaenops ocellatus) larvae exposed to environmental levels of atrazine and malathion, Aquatic Toxicology, vol.88, issue.4, pp.220-229, 2008.
DOI : 10.1016/j.aquatox.2008.05.001

I. Misumi, A. T. Vella, J. C. Leong, T. Nakanishi, and C. B. Schreck, p,p???-DDE depresses the immune competence of chinook salmon (Oncorhynchus tshawytscha) leukocytes, DDE depresses the immune competence of chinook salmon (Oncorhynchus tshawytscha) leukocytes, pp.97-114, 2005.
DOI : 10.1016/j.fsi.2004.11.005

, 21

J. M. Monserrat, P. E. Martinez, L. A. Geracitano, L. Lund-amado, C. Martinez-gaspar-martins et al., Pollution biomarkers in estuarine animals: Critical review and new perspectives, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol.146, issue.1-2, pp.1-2, 2007.
DOI : 10.1016/j.cbpc.2006.08.012

D. Nacci, M. Huber, D. Champlin, S. Jayaraman, S. Cohen et al., Evolution of tolerance to PCBs and susceptibility to a bacterial pathogen (Vibrio harveyi) in Atlantic killifish (Fundulus heteroclitus) from New Bedford (MA, USA) harbor, Environmental Pollution, vol.157, issue.3, pp.857-864, 2009.
DOI : 10.1016/j.envpol.2008.11.016

L. M. Pinchuk, S. Lee, and N. M. Filipov, In vitro atrazine exposure affects the phenotypic and functional maturation of dendritic cells, Toxicology and Applied Pharmacology, vol.223, issue.3, pp.206-217, 2007.
DOI : 10.1016/j.taap.2007.06.004

C. M. Press and Ø. Evensen, The morphology of the immune system in teleost fishes, Fish & Shellfish Immunology, vol.9, issue.4, pp.309-318, 1999.
DOI : 10.1006/fsim.1998.0181

S. Reynaud and P. Deschaux, The effects of polycyclic aromatic hydrocarbons on the immune system of fish: A review, Aquatic Toxicology, vol.77, issue.2, pp.229-238, 2006.
DOI : 10.1016/j.aquatox.2005.10.018
URL : https://hal.archives-ouvertes.fr/halsde-00295430

M. Roméo, N. Bennani, M. Gnassia-barelli, M. Lafaurie, and J. P. Girard, Cadmium and copper display different responses towards oxidative stress in the kidney of the sea bass Dicentrarchus labrax, Aquatic Toxicology, vol.48, issue.2-3, pp.185-194, 2000.
DOI : 10.1016/S0166-445X(99)00039-9

C. J. Secombes, The nonspecific immune system: cellular defenses in The fish immune system: organism, pathogen, and environment, pp.63-103, 1996.

. Seine-normandie-water and . Agency, Aisne Vesle Suippe. <http://www.eau-seinenormandie.fr/fileadmin/mediatheque/vallees- doise/ComGeo, 2007.

H. Teisseire, Toxicologie et écotoxicologie des pesticides et des métaux lourds susceptibles d'être présents dans le vignoble champenois : étude de leur impact physiologique et biochimique sur Lemna minor, p.272, 1999.

R. Van-der-oost, J. Beyer, and N. P. Vermeulen, Fish bioaccumulation and biomarkers in environmental risk assessment: a review, Environmental Toxicology and Pharmacology, vol.13, issue.2, pp.57-149, 2003.
DOI : 10.1016/S1382-6689(02)00126-6

J. T. Zelikoff, A. Raymond, E. Carlson, Y. Li, J. R. Beaman et al., Biomarkers of immunotoxicity in fish: from the lab to the ocean, Toxicology Letters, vol.112, issue.113, pp.112-113, 2000.
DOI : 10.1016/S0378-4274(99)00202-7

H. Zia, N. R. Harris, G. V. Merrett, M. Rivers, and N. Coles, The impact of agricultural activities on water quality: A case for collaborative catchment-scale management using integrated wireless sensor networks, Computers and Electronics in Agriculture, vol.96, pp.126-138, 2013.
DOI : 10.1016/j.compag.2013.05.001