Exposure assessment based recommendations to improve nanosafety at nanoliposome production sites

Abstract : The NANOFOL concept aims at creating nanodevices containing a drug for inflammatory disorder treatment. This paper provides recommendations for nanosafety based on a measurement campaign which aimed at identifying exposure risks with respect to two specific phases of the product's lifecycle, that is, production of the device and its waste management. The nanoparticle's presence both in air and in liquid phase was studied. While no emissions were detected during the production period, many recommendations have been made, particularly regarding the nanowaste treatment, based on nanosafety guidelines.