Utilisation des biomarqueurs pour la surveillance des rejets industriels : cas des effluents de l’industrie pharmaceutique

Abstract : Biomarkers are described as relevant parameters to assess the effects of aquatic ecosystems in wild fish species and could be used in environmental monitoring activities. In the present study, a set of biochemical and histological indicators was measured in wild gudgeon collected upstream and downstream of urban and pharmaceutical manufacture effluents. These individual end-points were associated to fish assemblage characterisation. Responses of these biomarkers revealed contamination of investigated stream by a mixture of pollutants. Fish from sampled sites downstream of the industrial effluent exhibited also strong signs of endocrine disruption including vitellogenin induction, intersex and male-biased sex-ratio. These individual effects were associated to a decrease of density and a lack of sensitive fish species. This evidence supports the hypothesis that pharmaceutical compounds discharged in stream are involved in recorded endocrine disruption effects and fish population disturbances and threaten disappearance of resident fish species. Overall, this study gives argument for the utilisation of an effect-based monitoring approach to assess impacts of pharmaceutical manufacture discharges on wild fish populations.
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Jean-Marc Porcher, Wilfried Sanchez. Utilisation des biomarqueurs pour la surveillance des rejets industriels : cas des effluents de l’industrie pharmaceutique. Rapport Scientifique INERIS, 2012, 2011-2012, pp.55-56. ⟨ineris-01869424⟩

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