Développement d’approches d’évaluation des dangers (éco)toxicologiques de substances émergentes issues de la chimie verte : les liquides ioniques.

Abstract : To reduce health and environmental risks of chemicals and to minimize the environmental footprint of human activities, green chemistry searches for alternative, environment-friendly reaction media and at the same time strives to increase reaction rates and milder reaction conditions. A growing area of research is devoted to ionic liquids often termed as “designer” solvents due to the extreme tunability of sought functional properties. However, these aspects have inadequately led many stakeholders to qualify ILs as ‘green solvents’. This qualification was stated without sufficient caution about versatility of ionic liquid chemical structures which could induce significant variation in risk profiles. Thus, the Institute proposed a potential industrial accompaniment to reduce ionic liquid harmfulness by a novel combination of OECD Daphnia magna standardized test and fish immunomarkers. The combination of these two tests allowed multicriteria examination of ILs impacts in different organisms and trophic levels. The work provided new data for legislation and opened a door towards an integrative environmental evaluation due to direct implications of immune system in fish and ecosystem health.
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Anne Bado-Nilles, Alpha-Oumar Diallo, Guy Marlair, Pascal Pandard. Développement d’approches d’évaluation des dangers (éco)toxicologiques de substances émergentes issues de la chimie verte : les liquides ioniques.. Rapport Scientifique INERIS, 2015, 2014-2015, pp.54-55. ⟨ineris-01869538⟩

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