Effet des radiofréquences sur des modèles de vulnérabilité cérébrale : développement et neuro-inflammation

Abstract : The widespread exposure of radiofrequency electromagnetic fields (RF-EMF) devices raises questions on their possible health consequences on the immature brain. Neuro-development is a period of sensitivity to environmental challenges such as inflammatory insults. Here, we assessed whether sensorymotor gating, emotionality, and novelty seeking were affected by RF-EMF exposures in fetus or adolescent rats, and tested whether maternal immune activation or adolescent neuroinflammation would increase RF-EMF toxicity. Rats were daily exposed to RF-EMF with loop antennas adjoining the abdomen of pregnant females (fetus body specific absorption rates (SAR): 0, 0.7 or 2.6 W/kg) or the head of adolescents (brain SAR: 0, 1.5 or 6 W/kg). Our result indicated that novelty seeking at adolescence was reduced after gestational exposure at 2.6 W/kg. Maternal immune activation induced a SAR-dependent reduction of sensory-motor gating in adults and adolescent neuroinflammation elicited a SAR-dependent reduction of emotionality. These data support the fact that special attention is needed for protection of developing organisms from combined environmental exposures with RF-EMF.
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Anne-Sophie Villegier. Effet des radiofréquences sur des modèles de vulnérabilité cérébrale : développement et neuro-inflammation. Rapport Scientifique INERIS, 2017, 2016-2017, pp.16-17. ⟨ineris-01869653⟩

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