Combined exposure to ultraviolet and radiofrequency radiation of reconstructed human skin model in vitro (SKIN-RF project)

Zsuzsanna Nemeth , Gyorgyi Kubinyi , Jozsef Bakos , Zsofia Szilagyi , Brahim Selmaoui (1, 2) , György Thuróczy

1 INERIS - Institut National de l'Environnement Industriel et des Risques
2 PERITOX - Périnatalité et Risques Toxiques - UMR INERIS_I 1

The aim of this study was to examine whether the combined exposure to solar ultraviolet (UV) radiation and radiofrequency (RF) exposure have any effect on cytokine (IL-1α, IL-6, IL-8) and MMP-1enzyme secretion on in vitro reconstructed human skin model. The full thickness skin models were exposed to UV radiation (2 SED, 4 SED) and radiofrequency (Wi-Fi, UMTS). The IL-1α, IL-6, IL-8 and MMP-1concentrations were measured 24 hours after UV and RF exposures from the culture media by the ELISA method. This experiment was done for the project named “Cellular response to co-exposure of radiofrequency (RF) and solar ultraviolet (UV) radiation in human in vitro skin model (SKIN-RF)”.

Domaines: Toxicologie

Zsuzsanna Nemeth, Gyorgyi Kubinyi, Jozsef Bakos, Zsofia Szilagyi, Brahim Selmaoui, et al.. Combined exposure to ultraviolet and radiofrequency radiation of reconstructed human skin model in vitro (SKIN-RF project). Annual meeting of the Bioelectromagnetics Society and the European BioElectromagnetics Association (BioEM 2019), Jun 2019, Montpellier, France. ⟨ineris-03229555⟩