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The european consensus platform for 3R alternatives to animal experimentation (ECOPA)

Abstract : The ecopa is a non-profit organization which explores all possible means to improve the exchange of information in the area of alternative methods. The primary mission of ecopa is to raise public, governmental and scientific awareness for a better use of alternative methods for scientific purposes with the final goal of fully replacing all in vivo tests while improving the quality of risk assessment in humans. Presently, ecopa is composed by 7 National Consensus Platforms (French, Finland, Norway, Spain, Italy, Germany and Switzerland) and has other members as individuals to include academic institutions, professional associations, companies, and any other organisation (or one of its divisions) which support ecopa's aims. National Consensus Platforms are usually structured with representatives from ecopa’s four stakeholders: Government and regulatory authorities, academia, industry, and animal protection and welfare organisations. The aims of ecopa are to facilitate the exchange of scientific information, expertise and experience between national consensus platforms to enhance implementation of refinement, reduction and replacement in the EU and worldwide. ecopa recommends the use of alternative strategies that may elucidate the real mechanism of actions of the different substances in humans, in particular when the animal models fail in predicting an effect. This is particularly true in the area of drug development where so many differences exist between humans and animals. Adhering to the 3Rs, ecopa strives to raise public, governmental and scientific awareness for a better acceptance of alternatives both at member state and European levels. Members of ecopa are part of ESAC at EURL-ECVAM and it is constantly in contact with DG Environment and DG Health & Consumers. Additionally, many members are participating in European Integrated Projects. The ecopa is also an accredited stakeholder at ECHA. Some national consensus platforms also have strong interest in the food and feed sectors even though the main focus remains in the methodology for risk assessment. New Approach Methodologies (NAMs) integrating advanced in vitro, in silico and in chemico tools should be developed and included in testing strategies to increase our understanding of toxicity mechanisms in humans and the risks to the environment. The same goal applies to biomedical research. ecopa’s strategic goals apply to all areas where animals are used for scientific or regulatory purposes.
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Submitted on : Thursday, May 27, 2021 - 2:38:32 PM
Last modification on : Friday, May 28, 2021 - 3:11:36 AM


  • HAL Id : ineris-03239403, version 1



Costanza Rovida, L. Bastos, Philippe Hubert, T. Heinonen. The european consensus platform for 3R alternatives to animal experimentation (ECOPA). ECOPA 2018 Symposium "How new experimental tools in life sciences challenge the 3Rs vision", Nov 2018, Paris, France. pp.46. ⟨ineris-03239403⟩



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