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Low‐Level Radiofrequency Exposure Induces Vasoconstriction in Rats

Abstract : Recent studies have revealed that rodents' physiological responses to low-intensity radiofrequency (RF) electromagnetic fields were similar to thermoregulatory responses to cold conditions. The primary autonomic response to cold exposure is peripheral vasoconstriction that allows rodents to reduce heat loss and maintain a relatively constant internal body temperature. In the present study, we investigated the effects of 900 MHz RF at a low level (SAR of 0.35 W/kg) on tail skin temperature (Ttail ) in rats. We showed that rats exposed to RF had lower Ttail than control rats at ambient temperatures between 27 and 28 °C, suggesting that RF could induce a noticeable degree of vasoconstriction under mild-warm ambient temperatures. This difference in Ttail was suppressed after the intraperitoneal injection of a vasodilator, an α-adrenergic antagonist, confirming the hypothesis of the vasoconstriction in exposed rats. Moreover, like a response to cold stimuli, RF exposure led to increased plasma concentrations of important factors: noradrenaline (a neurotransmitter responsible for vasoconstriction and thermogenesis) and fatty acids (markers of activated thermogenesis). Taken together, these findings indicate that low-intensity RF levels triggered some key physiological events usually associated with responses to cold in rats.
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Submitted on : Wednesday, June 30, 2021 - 12:43:44 PM
Last modification on : Friday, August 5, 2022 - 11:25:43 AM
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Thi Cuc Mai, Anne Braun, Véronique Bach, Amandine Pelletier, René de Seze. Low‐Level Radiofrequency Exposure Induces Vasoconstriction in Rats. Bioelectromagnetics, 2021, ⟨10.1002/bem.22350⟩. ⟨ineris-03246969⟩



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