Towards FAIR nanosafety data

Nina Jeliazkova , Margarita Apostolova , Cristina Andreoli , Flavia Barone , Andrew Barrick , Chiara Battistelli , Cecilia Bossa , Alina Botea-Petcu , Amélie Châtel , Isabella de Angelis , Maria Dusinska , Naouale El Yamani , Daniela Gheorghe , Anna Giusti , Paloma Gómez-Fernández , Roland Grafström , Maciej Gromelski , Nicklas Raun Jacobsen , Vedrin Jeliazkov , Keld Alstrup Jensen , Nikolay Kochev , Pekka Kohonen , Nicolas Manier (1) , Espen Mariussen , Agnieszka Mech , José María Navas , Vesselina Paskaleva , Aurica Precupas , Tomasz Puzyn , Kirsten Rasmussen , Peter Ritchie , Isabel Rodríguez Llopis , Elise Rundén-Pran , Romica Sandu , Neeraj Shandilya (2) , Speranta Tanasescu , Andrea Haase , Penny Nymark

1 INERIS - Institut National de l'Environnement Industriel et des Risques
2 TNO - The Netherlands Organisation for Applied Scientific Research

The proposal of a FAIR-aligned Nanosafety Data Interface can advance findability, accessibility and interoperability across physicochemical, bio-nano interaction, human toxicity, omics, ecotoxicological and exposure data. Nanotechnology is a key enabling technology with billions of euros in global investment from public funding, which include large collaborative projects that have investigated environmental and health safety aspects of nanomaterials, but the reuse of accumulated data is clearly lagging behind. Here we summarize challenges and provide recommendations for the efficient reuse of nanosafety data, in line with the recently established FAIR (findable, accessible, interoperable and reusable) guiding principles. We describe the FAIR-aligned Nanosafety Data Interface, with an aggregated findability, accessibility and interoperability across physicochemical, bio-nano interaction, human toxicity, omics, ecotoxicological and exposure data. Overall, we illustrate a much-needed path towards standards for the optimized use of existing data, which avoids duplication of efforts, and provides a multitude of options to promote safe and sustainable nanotechnology.

Domains: Environmental Sciences

Nina Jeliazkova, Margarita Apostolova, Cristina Andreoli, Flavia Barone, Andrew Barrick, et al.. Towards FAIR nanosafety data. Nature Nanotechnology, 2021, 16 (6), pp.644-654. ⟨10.1038/s41565-021-00911-6⟩. ⟨ineris-03267556⟩